4395394 Use of lipid amines formulated with fat or lipid emulsions as vaccine adjuvants

4395394 Use of lipid amines formulated with fat or lipid emulsions as vaccine adjuvants

359 PATENT ABSTRACTS response. Preferred compositions employ N, Nhigher alkyI-N',N'-bis(2hydroxyethyl)propanediamines, particularly N, N-dioctadecyI...

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359

PATENT ABSTRACTS response. Preferred compositions employ N, Nhigher alkyI-N',N'-bis(2hydroxyethyl)propanediamines, particularly N, N-dioctadecyI-N'.N'-bis(2-hydroxyethyl)propanediamine in lntralipid.

4393133 HUMAN HEPATOMA DERIVED CELL LINE, PROCESS FOR PREPARATION THEREOF, AND USES THEREFOR Barbara B Knowles. David P Aden assigned to The Wistar Institute of Anatomy and Biology

4394502 IMMUNOTHERAPEUTIC AGENT FOR TUMORS COMPRISING L I P O P O L Y S A C C H A R I D E AS AN ACTIVE COMPONENT

Human hepatoma cell lines, useful for metabolic studies such as screening potential carcinogens and mutagens, for cultivation of viruses, and for preparation of vaccines is obtained by culturing human hepatocarcinoma or hepatoblastoma on lethally irradiated cell feeder layers in the presence of a culture medium.

ChisatoMaruyama, Mukogaoka, Bunkyo ku, Tokyo to, Japan Disclosed is a novel immunotherapeutic agent for tumors, which comprises as an active component a lipopolysaccharide derived from human tubercle bacillus or a lipopolysaccharide formed by chemically modifying said lipopolysaccharide.

4393071 METHOD OF TREATING GASTRIC, MAMMARY, LUNG AND UTERUS TUMORS Naoharu Fujii, Noboru Iijim& assigned to Shibuya ku. Tokyo, Japan

4394446 PROCESS FOR THE PREPARATION OF THE ANTIBIOTIC OXANOSINE Hama Umezawa, Nobuyoshi Shimada, Hiroshi Naganawa, Tomohisa Takita, Masa Hamada, Tomio Takeuchi, Tokyo, Japan assigned to Zaidan Hojin Biscibutsu Kagnku Kenkyu Kai The novel antibiotic, oxanosine, having the structure See Patent for Chemical Structure inhibits the growth of Gram-negative bacteria and has antiviral and carcinostatic activity. It is produced by cultivation of an oxanosine-producing microorganism of the genus Streptomyces, preferably Streptomyces capreolus MG265-CF3, ATCC No. 319.63.

A method of treating malignant tumors by daily administering of between 5 and 100 mg of protoporphyrin. Prcferrably the protoporphyrin is given with a carrier which can be a solid edible material. 4393056 ANTIBIOTICS TETRONOLIDE COMPOUNDS AND PROCESS FOR PRODUCTION THEREOF

Fusao Tomita, Tatsuya Tamaoki, Kunikatsu Shirahata, Masaji Kasai, Noriaki Hirayama, Makoto Morimoto, Masanori Fukui, Machida, Japan assignedto Kyowa Hakko Kogyo Co Ltd New antibacterial tetronolide compounds F-I and F-2 are produced by fermentation of a