OOOO Volume 129, Number 1 clear halos, mitotic figures, and mitosoid cells. The underlying connective tissue presented scarce inflammatory cells. The data confirmed the original clinical hypothesis of multifocal epithelial hyperplasia (Heck disease). No treatment was performed because of the self-limited characteristics of the disease. The patient is now under 6-month follow-up, already showing early signs of lesion remission.
ADENOID CYSTIC CARCINOMA: A CASE REPORT. BARBARA MARTINS ANDRADE, SARA FERREIRA DOS SANTOS COSTA, ANDRE MYLLER BARBOSA SILVA, FELIPE PAIVA ^ A PONTES, FONSECA, FLAVIA SIROTHEAU CORRE ^ LUCAS LACERDA DE SOUZA and, HELDER ANTONIO REBELO PONTES Adenoid cystic carcinoma is the most common malignant salivary gland tumor in most of the studies. It can affect any salivary gland, but it more commonly involves the minor salivary glands of the palate and the parotid glands, presenting as an asymptomatic slow-growing swelling in middle-aged adults. The aim of this report is to present a case of adenoid cystic carcinoma affecting a 45-year-old female patient that demonstrated a painful swelling on the floor of the mouth. The microscopic analysis revealed a salivary gland neoplasm involving the submandibular gland presenting a cribriform architectural growth pattern with the presence of basaloid and hyperchromatic neoplastic cells. Perineural infiltration was also found. Immunohistochemical positivity for AE1/AE3, CK14, and smooth muscle actin was observed, and a low proliferative index measured by Ki67 expression was seen. The patient was then referred for oncologic treatment and is under follow-up in our department. Support: FAPEMIG
PRIMARY DIFFUSE LARGE B-CELL LYMPHOMA OF THE MANDIBLE: A RARE CASE ^ REPORT. GABRIELA ALVES RIBEIRO, VANIA BRAGA MOLERI, DO CARMO RODRIGUES, ANDREA LUISA AGUIRRE BUEXM, LUCIANA WERNERSBACH PINTO, ADRIANA TEREZINHA NEVES NOVELLINO ALVES and, SIMONE DE QUEIROZ CHAVES LOURENCO ¸ Diffuse large B-cell lymphoma is a malignant neoplasm of the lymphoid system and represents the majority cases of nonHodgkin lymphomas. Nevertheless, it is a low-rate event in the head and neck region, especially as a primary occurrence. This is a case report of a primary extranodal diffuse large B-cell lymphoma in the mandible of a 52-year-old male patient who had no previous neoplasm history. Clinical examination and image examinations evidenced an asymptomatic singular intraosseous lesion in the mandibular bone measuring 5 cm, presenting oneand-a-half-year evolution. Odontogenic myxoma was clinical diagnostic hypothesis, and an incisional biopsy was performed. Microscopy was compatible with malignant neoplasm and immunohistochemical analysis was positive for CD20, PAX5, CD3, CD4, and CD10 markers, concluding the diagnosis of diffuse large B-cell lymphoma. The patient was treated with 4 cycles of rituximab plus cyclophosphamide, doxorubicin (hydroxydaunorubicin), vincristine (Oncovin), and prednisone chemotherapy protocol. He responded very positively to the treatment and is still under follow-up.
LEISHMANIASIS IN LABIAL MUCOSA: CASE REPORT. LORENA BATISTA SANDRE, JOSE WILLIAM SANTOS DE OLIVEIRA PINTO, ALESSO CERVANTES SARTORELLI and, ELIZIARIO e CESAR DE VASCONCELOS LEITAO Leishmaniasis is a serious problem of public health in Brazil and in the world. Caused by protozoa, it occurs more frequently in cutaneous form. Rarely, when it affects the oral mucosa, the disease is destructive or ulcerous-vegetative and granulomatous. This study reports the case of a 34-year-old patient with an ulcerated lesion with significant adjacent edema throughout the lower lip measuring about 3 cm with an asymptomatic evolution of 3 months, defined limits, rounded shape, reddish and yellowish color, and normal consistency. An incisional biopsy of the lesion was performed, and the material was sent for histopathologic and immunohistochemical analysis; which showed a lesion exhibiting lymphoid, hystiocytic and plasma cell infiltration, occupying the entire mucosal chorion, containing numerous structures with leishmania characteristics. The final diagnosis was mucocutaneous leishmaniasis. The patient underwent clinical and medical treatment with dermatologist, showing no signs of recurrence after 1 year.
FIBROMYXOMA IN THE MANDIBLE: CASE ^ BARROS, REPORT. ANA WALESKA PESSOA KEYLA MOURA ROCHA TORRES, LUCAS NASCIMENTO RIBEIRO, ROBERTO VIEIRA DE MELO, RAISSA SOARES DOS ANJOS, IGOR HENRIQUE ^ MORAIS SILVA and, ROMULO OLIVEIRA DE HOLLANDA VALENTE A 7-year-old black male child complained of increased volume in the face with no relevant medical history. Extraoral physical examination showed an increased volume in the jaw body of the left side, hard to palpation and with unknown evolution time. A painless hard volume increase at the palpation of the vestibule was in the mouth. Computed tomography scan revealed a solid expansive lesion by inflating the vestibular cortical of the jaw body to the left. Incisional biopsy was performed, and the histologic slices stained in hematoxylin and eosin showed a pattern of spindle cells arranged in regular bundles in addition to mitochondrial areas with little cellularity. Immunohistochemistry was positive for vimentin and Ki67 (4%) and negative for smooth muscle actin, desmin, S100, CD34, and caldesmon, leading to a diagnosis of fibromyxoma. The mandibulectomy was performed associated with application of liquid nitrogen for 3 months without signs of local recurrence.
MAJOR APHTHOUS ULCERATIONS ASSOCIATED WITH SICKLE CELL ANEMIA EXACERBATED BY ORTHODONTIC TREATMENT. FLAVIO LUCENA ANTUNES, PAULO EDUARDO ALENCAR DE SOUZA, GIOVANNA RIBEIRO SOUTO, HELENICE DE ANDRADE MARIGO GRANDINETTI, MARTINHO CAMPOLINA REBELLO HORTA and, SORAYA DE MATTOS CAMARGO GROSSMANN An 18-year-old white woman was referred to our service with complaint of “ulcerations on the tongue.” The lesions worsened in the last 6 months when the orthodontic appliance was placed. The patient was vegetarian, and she reported a prolonged menstrual period. Oral examination revealed multiple