Answers to CME examination

Answers to CME examination

456 Journal oi~the American Academy of Dermatology CME examination 14. Each of the following is an inhibitor of viral reverse transcriptase except ...

74KB Sizes 2 Downloads 55 Views

456

Journal oi~the American Academy of Dermatology

CME examination

14. Each of the following is an inhibitor of viral reverse transcriptase except a. ansamycin b. suramin sulfate c. HPA-23 d. phosphonoformate e. AS 101 15. Hypericin and pseudohypericin are thought to interfere with a. initial binding of the HIV-1 virus to the cell surface b. viral reverse transcfiptase c. viral endonuclease (integrase) activity at the level of chromatin d. provirus formation e. viral assembly, budding or shedding at the cell surface 16. In the attempt to produce a vaccine against HIV-1, the option of an attenuated whole-virus vaccine has been virtually eliminated because a. of the risk of infection with hepatitis B virus b. of the risk of infection with hepatitis non-A non-B virus c. of the risk of development of the acquired immunodefieiency syndrome from the virus d. disabled retroviral genetic material could induce malignancy e. of regulations of the Food and Drug Administration that prohibit administration of recembinant genetic material to healthy humans

Directions for questions 17-21: For each numbered item choose the appropriate lettered item.

17. 18. 19. 20. 21.

a. Zidovudine b. 2 j, 3 '-Dideoxycytidine c. Both d. Neither Inhibitor of viral reverse transcriptase Produces chain termination Associated with a neuropathy Associated with bone marrow toxicity Associated with pain as an important complication

Directions for questions 22 and 23: For each numbered item choose the appropriate lettered item. a. Heparin sulfate b. Dextran sulfate c. Both d. Neither 22. Potent and selective inhibitor of I-IIV- 1 in vitro 23. Concentrations of the virus sufficient to inhibit the HIV-1 virus in vivo would be likely to interfere with coagulation.

Directions for questions 24 and 25: For each numbered item choose the appropriate lettered item. a. CD4-cytotoxin hybrids b. CD4-IgG hybrids c. Both d. Neither 24. Targeted against the free HIV-1 virus 25. Expected to kill latently infected cells

Answers to CME examination*

Identification No. 889-108

August 1989 issue of the JOURNALOF THE AMERICANACADEMYOFDERMATOLOGY Questions 1-33, Abel EA. J AM ACAD DERMATOL 1989;21:167-79. 1. b (p 167, c 2, pa 1) 2. e (p 167, c 2, pa 1--p 168, c 1, pa 1) 3. c (p 168, c 1, pa 2) 4. d (p 168, c 1, pa 2) 5. d (p 170, c 1, pa 4) 6. c (p 170, c 2, pa 1) 7. b (p 171, c 1, pa 3) 8. b (p 171, c 1, pa 3) 9. b (p 171, e 1, pa 5---c 2, pa 1) 10. e (p 173, c 2, pa 3) 11. d (p 173, c 1, pa 2) 12. e (p 175, c 1, pa 2) 13. b (p 175, e 2, pa 3) 14. d (p 176, c 1, pa 1) 15. d (p175, c2, pa4) 16. c (p176, e l , p a 2 ) *p: page;e: column;pa: paragraph.

17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33.

b e d c a d c a b c a, e a, b, d c, e c, e a,b,c,d,e a,b,e,d,e a, d

(p 176, e 2, pa (p 176, c 2, pa (p 176, c 1, pa (p 168, c 1, pa (p 168, c 1, pa (p 168, c 1, pa (p 172, c 2, pa (p 170, c 1, pa (p 177, c 1, pa (p 177, c 1, pa (p 167, c 1, pa (p 167, c 1, pa (p 167, c 1, pa (p 170, c2, pa (p171, c 1, pa (p174, c 2, pa (p 177, c 1, pa

2--pa 3) 2) 3) 3---c 2, pa 1) 3---c 2, pa 1) 3----c 2, pa 1) 1) 2; p 172, c 2, pa 1) 2) 2) 2) 2) 2) 1) 3) 1--p 175, c 1, pa 1) 3)