Chemobiodynamics and Drug Design. By F. W. SCHUELER. The Blakiston Division, McGrawHill Book Co., Inc., 330 West 42nd St., New York 36, N. Y., 1960. 15 × 23 cm. Price $19.50.xiv + 638 pp.

Chemobiodynamics and Drug Design. By F. W. SCHUELER. The Blakiston Division, McGrawHill Book Co., Inc., 330 West 42nd St., New York 36, N. Y., 1960. 15 × 23 cm. Price $19.50.xiv + 638 pp.

92 Journal of Pharmaceutical Sciences Internationales Biguanid-Symposium. Edited by F. BERTRAM and G. MICHAEL. Georg Thieme Verlag, Stuttgart, Germa...

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92

Journal of Pharmaceutical Sciences

Internationales Biguanid-Symposium. Edited by F. BERTRAM and G. MICHAEL. Georg Thieme Verlag, Stuttgart, Germany, 1960. Available in the U. S. and Canada from Intercontinental Medical Book Co., 381 Fourth Ave., New York, 16, N. Y. vii I67 pp. 15.5 X 23 cni. Paperbound. Price$4. Reports and discussions on these with biguanides, including phenformin (DBI), are compiled from the 1960 symposium held a t Aachen. All reports are in German, including two by U. S. groups, except one discussion by H. S. Sadow of New York which was not translated from the English.

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American Pharmacy. 5th ed. Edited by JOSEPH B. SPROWLS.Medical Dept., J. B. Lippincott Co., East Washington Square, Philadelphia 5, Pa., 1960. xxiii 493 pp. 18 X 25.5 em. Price $10.75. The fifth edition of this textbook of pharmaceutical principles, processes, and preparations has incorporated the changes necessary t o bring it into agreement with U. S. P. XVI, N. F. XI, and the N. N. D. 1960.

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Biology Code of the Chemical-Biological Coordination Center. Vol. I, Code. Vol. 2, Key to the Code. Edited by PHILIP G. SEITNER. National Acadlilirafiltration. By L. AMBARDand S. TRAUTMANN. emy of Sciences; National Research Council, Charles C Thomas, 301-327 East Lawrence Washington 25, D. C., 1960. Vol. 1, viii 222 pp. 1’01. 2, iv 210 pp. 21.5 X 27.5 cm. Ave., Springfield, Ill., 1960. x 67 pp. 15.5 Paperbound. Price $12 a set or $7 each volume. X 23 cm. Price $4.50. Also available in cloth binding. Professor A. M. Monnier who translated this Developed by the Chemical Biological Coordinamonograph from French t o English notes in the preface that Ambard’s hook contains much more tion Center, the code was used for coding (indexing) than the title indicates; it is a “reappraisal of fun- the collected information for IBM punched card damentals” introducing entirely new concepts. storage. The data collected from 1945 until the Center was terminated in 1957 covers the chemicalTheories and experimental results in ultrafiltration biological fields (pharmaceutical and clinical, plant are related to biological phenomena. Monnier states that even if one is opposed to the views growth regulation, insecticide, etc.) Volume 1 developed by Ambard, he will realize that current contains the series of classification schemes, code theories do not offer any straightforward account itetns, and code symbols. Volume 2, “Key to the Biology Code,” describes each of the lists and gives of the curious phenomena presented by ultrafiltration. explanations and instructions for the use of the code symbols.

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The Dispensatory of the United States of America. Vol. 2. New Drug Developments. Edited by ARTHUROSOL and ROBERTSON PRATT. Medical Dept., J. B. Lippincott Co., East Washington Square, Philadelphia 5, Pa., 1960. 210 pp. 17.5 X 26 cm. Price 99. Volume 2 of U. S. D. 25 is mainly devoted to providing information concerning more than 200 new drugs and their many dosage forms that have been introduced since the publication of U. S. D. volume 1, in 1955. New information about certain drugs already described in volume 1, and general survey articles on antibiotics, antibiotics with antitumor activity, hypoglycemic sulfonylureas and biguanides, psychotherapeutic and psychotomimetic drugs, and saluretic agents are included. Chemical and trade names are given immediately under the generic title of each monograph. The concise thoroughness of U. S. D. is maintained.

Chemobiodynamics and Drug Design. By F. W. SCHUELER.The Blakiston Division, McGrawHill Book Co., Inc., 330 West 42nd St., New York 36, N. Y., 1960. xiv 638 pp. 15 X 23 cm. Price $19.50. The principles of chemical control in biology are applied by the author to the problems of drug design. Part 1, entitled “Chemobiodynamics,” emphasizes the structural and functional relationship of chemistry to biology and its antecedents. Part 2 emphasizes the nature of drug design as an activity preceding drug synthesis. The relationship between chemical constitution and pharmacological activity is developed throughout the text, and the fundamentals of drug action is well presented. References are given in the text and an index is appended.

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Lipide Metabolism. Edited by KONRADBLOCH. John Wiley 8r Sons, Inc. 440 Fourth Ave., New Essentials of Pharmacology. 4th ed. By FRANCES York 16, N. Y., 1960. xiii 411 pp. 15 X 23 K. OLDHAM, F. E. KELSEY,andE. M. K. GEILING. cm. Price $10.50. Medical Dept.. J. B. Lippincott Co., East WashPlanned as a companion t o Hanahan’s “Lipide ington Square, Philadelphia 5, Pa., 1960. xiv Chemistry” this book is a series of contributions 418 pp. 15 X 23 cm. Price $7.75. dealing with the transformations of lipides by living A concise, yet broad survey of pharmacology is systems and by isolated enzymes. The text is presented for the undergraduate student. Added divided under the headings: Enzymatic mechanisms in this edition is a chapter on hallucinogens and of fatty acid oxidation and synthesis, Metabolism of tranquilizers, and a section on monoamine oxidase unsaturated fatty acids, Metabolism and function of inhibitors under CNS stimulants. Although the phosphatides, Metabolism of glycerides, Lipolytic existence of U. S. P. XVI and N. F. X I are recog- enzymes, Hormonal regulation of fatty acid metabonized in chapter 3, page 16, the preparations listed lism, Formation and metabolism of bile acids, and a t the end of each chapter were compiled from U. Chemistry and metabolism of bacterial lipides. S. P. XV and N. F. X in addition to the B. P. and References are given, alphabetically, a t the end of N. N. D. each chapter, and an index is appended.

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