501 " XBD=2282 XBD=1592 XBD=1644 XBD=1908 XBD=2166 XHG=1453 XHG=1602 XHG=1653 XHG=1919 XHG=2176 YBD=325 YHG=301>AFTER YBD=324 YBD=323 YHG=303>RELAPSE ...

163KB Sizes 2 Downloads 49 Views


MENINGITIS |>" " XBD=1608 XBD=1771 XBD=1815 XBD=1906 XBD=2246 XBD=2348 XBD=2040 XHG=1387 XHG=1619 XHG=1782 XHG=1826 XHG=2050 XHG=2264 XHG=1917 YBD=369 YBD=368 YBD=375 YBD=373 YBD=379 YHG=348>GLUCANTIME YHG=347>THERAPY YHG=348>IN YHG=342>TRES YHG=346>(DECEMBER, YHG=341>1985) YHG=347>BRACOS " XBD=1207 XBD=249 XHG=898 XBD=320 XBD=415 XBD=458 XBD=539 XBD=584 XBD=643 XBD=812 XBD=886 XBD=945 XBD=1109 XHG=129 XHG=262 XHG=335 XHG=426 XHG=471 XHG=552 XHG=596 XHG=656 XHG=826 XHG=958YBD=437 XHG=1121 YBD=445 YBD=446 YBD=439 YBD=438 YBD=438 YBD=446 YHG=410>SIR,-It YHG=419>was YHG=410>good YHG=417>to YHG=410>find YHG=409>in YHG=408>Schifferli YHG=409>and YHG=409>Dr YHG=409>Herschel YHG=409>(Nov " XBD=1205 XBD=141 XHG=797 XBD=176 XBD=277 XBD=356 XBD=472 XBD=564 XBD=650 XBD=716 XBD=783 XBD=961 XBD=1068 XHG=98 XHG=157 XHG=193 XHG=291 XHG=371 XHG=487 XHG=579 XHG=664 XHG=731 XHG=978 XHG=1082 YBD=490 YBD=492 YBD=483 YBD=481 YBD=482 YBD=490 YBD=490 YHG=457>30, YHG=464>p YHG=454>1240) YHG=454>that YHG=455>others YHG=454>have YHG=453>read YHG=453>the YHG=453>old YHG=453>literature. YHG=454>They YHG=460>suggest " XBD=1205 XBD=155 XHG=856 XBD=219 XBD=357 XBD=416 XBD=529 XBD=621 XBD=718 XBD=800 XBD=836 XBD=976 XHG=97 XHG=175 XHG=239 XHG=378 XHG=440 XHG=551 XHG=641 XHG=739 XHG=820 XHG=996 YBD=529 YBD=527 YBD=534 YBD=526 YBD=533 YBD=534 YHG=500>that YHG=499>Dr YHG=498>George YHG=499>D. YHG=498>Heist YHG=507>may YHG=497>have YHG=497>had YHG=507>a YHG=498>genetic YHG=497>complement " XBD=1205 XBD=263 XHG=823 XBD=396 XBD=537 XBD=805 XBD=926 XBD=1001 XBD=1091 XBD=1137 XHG=97 XHG=280 XHG=412 XHG=554 XHG=940 XHG=1017 XHG=1105 XHG=1152 YBD=580 YBD=571 YBD=578 YBD=570 YBD=571 YBD=579 YBD=570 YHG=543>deficiency. YHG=542>Heist’s YHG=542>familial YHG=541>predisposition, YHG=541>which YHG=551>was YHG=541>only YHG=542>in YHG=541>the " XBD=1793 XBD=181 XHG=889 XBD=258 XBD=405 XBD=454 XBD=567 XBD=737 XBD=816 XBD=868 XBD=964 XBD=1154 XBD=1204 XHG=96 XHG=200 XHG=277 XHG=424 XHG=475 XHG=587 XHG=757 XHG=837 XHG=982 XHG=1172 YBD=617 YBD=616 YBD=624 YBD=615 YBD=614 YBD=622 YBD=624 YBD=615 YHG=588>males YHG=596>was YHG=586>claimed YHG=596>as YHG=586>being YHG=585>probably YHG=586>due YHG=592>to YHG=586>IgM YHG=586>deficiency YHG=586>in " XBD=1337 XBD=1464 XBD=1528 XBD=1659 XHG=1304 XHG=1349 XHG=1475 XHG=1540 XHG=1670 YBD=621 YBD=622 YBD=628 YHG=597>*2 YHG=596>patients YHG=596>had YHG=596>mucosal YHG=596>relapses.

" XBD=1090 XBD=1204XHG=576 XBD=191 XBD=310 XBD=460 XBD=556 XBD=766 XBD=1037 XHG=99 XHG=217 XHG=331 XHG=480 XHG=787YBD=661 XHG=1057 XHG=1110 YBD=660 YBD=659 YBD=668 YBD=658 YBD=659 YHG=624>1967.1 YHG=631>Other YHG=631>families YHG=630>with YHG=630>inheritance YHG=630>predominantly YHG=630>in YHG=630>males XBD=166 XBD=322 XBD=366 XBD=447 XBD=549 XBD=632 XBD=681 XBD=714 XBD=855 XBD=913 XBD=961 XBD=1112 XHG=922 XHG=95 XHG=181 XHG=338 XHG=383 XHG=464 XHG=572 XHG=648 XHG=697 XHG=730 XHG=978 XHG=1128 YBD=705 YBD=702 YBD=704 YBD=703 YBD=711 YBD=704 YHG=685>were YHG=675>recorded YHG=681>at YHG=675>that YHG=667>timel YHG=674>and YHG=674>in YHG=684>a YHG=667>review2 YHG=674>of YHG=675>89 YHG=675>subjects YHG=674>with " XBD=1204 XBD=1337XHG=875 XBD=1391 XBD=1558 XBD=1736 XBD=1839 XBD=1908 XBD=2001 XBD=2091 XBD=2140 XBD=2209 XBD=2284 XBD=2435 XHG=1305 XHG=1353 XHG=1408 XHG=1577 XHG=1753 XHG=1856 XHG=1924 XHG=2017 XHG=2108 XHG=2156 XHG=2228 XHG=2301 YBD=706 YBD=705 YBD=714 YHG=683>to YHG=676>be YHG=669>defined.6 YHG=675>Antibody YHG=676>titres YHG=675>fell YHG=675>with YHG=676>time YHG=676>in YHG=677>the YHG=678>125 YHG=676>patients

XBD=219 XHG=884 XBD=356 XBD=442 XBD=626 XBD=817 XBD=871 XBD=900 XBD=1033 XBD=1138 XBD=1203 XHG=95 XHG=232 XHG=369 XHG=455 XHG=638 XHG=830 XHG=914YBD=758 XHG=1046 XHG=1151 YBD=756 YBD=747 YBD=748 YBD=755 YBD=756 YBD=748 YHG=721>primary YHG=719>isolated YHG=719>IgM YHG=719>deficiency YHG=718>(presumed YHG=728>on YHG=728>a YHG=719>genetic YHG=719>basis) YHG=719>the " XBD=2434 XBD=1450 XBD=1499 XBD=1597 XBD=1634 XBD=1723 XBD=1908 XBD=2015 XBD=2118 XBD=2259 XBD=2315 XBD=2378 XHG=1305 XHG=1467 XHG=1517 XHG=1613 XHG=1654 XHG=1740 XHG=1924 XHG=2032 XHG=2134 XHG=2277 XHG=2325 XHG=2394 YBD=758 YBD=757 YBD=749 YBD=759 YBD=750 YHG=720>analysed YHG=721>in YHG=720>table YHG=727>1. YHG=720>The YHG=720>geometric YHG=729>mean YHG=721>titres YHG=721>(GMT) YHG=721>of YHG=721>the YHG=722>42 XBD=283 XHG=781 XBD=551 XBD=632 XBD=713 XBD=761 XBD=951 XBD=1159 XBD=1203 XHG=96 XHG=302 XHG=571 XHG=651 XHG=734 XHG=969 XHG=1178 YBD=794 YBD=801 YBD=791 YBD=792 YBD=792 YBD=791 YHG=764>male:female YHG=764>preponderance YHG=772>was YHG=763>4:1. YHG=762>A YHG=763>sex-linked YHG=763>inheritance YHG=762>isat " XBD=2433 XBD=1437 XBD=1529 XBD=1682 XBD=1814 XBD=1908 XBD=1977 XBD=2049 XBD=2117 XBD=2205 XBD=2259 XHG=1305 XHG=1453 XHG=1545 XHG=1697 XHG=1829 XHG=1924 XHG=1987 XHG=2065 XHG=2132 XHG=2220 XHG=2267 YBD=801 YBD=793 YBD=795 YBD=794 YBD=802 YHG=765>patients YHG=765>with YHG=764>mucosal YHG=765>disease YHG=774>were YHG=766>27.7 YHG=766>7 YHG=764>the YHG=765>time YHG=765>of YHG=765>diagnosis, " XBD=2431 XBD=234 XHG=936 XBD=340 XBD=388 XBD=440 XBD=517 XBD=572 XBD=634 XBD=797 XBD=919 XBD=974 XBD=1113 XBD=1203 XHG=94 XHG=251 XHG=356 XHG=404 XHG=458 XHG=534 XHG=583 XHG=651 XHG=814 XHG=984 XHG=1128 YBD=838 YBD=845 YBD=835 YBD=836 YBD=836 YHG=808>therefore YHG=807>likely YHG=814>to YHG=808>be YHG=816>one YHG=806>the YHG=816>common YHG=816>causes YHG=806>of YHG=807>isolated YHG=807>IgM XBD=1442 XBD=1520 XBD=1606 XBD=1670 XBD=1863 XBD=1952 XBD=2104 XBD=2312 XHG=1368 XHG=1467 XHG=1546 XHG=1632 XHG=1689 XHG=1891 XHG=2019 XHG=2130 XHG=2344 YBD=843 YBD=846 YBD=844 YBD=838 YHG=810>3 YHG=809>the YHG=809>end YHG=809>of YHG=815>treatment, YHG=809>and YHG=809>8 YHG=809>December, YHG=810>1985. at by XBD=260 XHG=852 XBD=341 XBD=463 XBD=580 XBD=730 XBD=797 XBD=833 XBD=972 XBD=1151 XBD=1208 XHG=94 XHG=281 XHG=359 XHG=482 XHG=599 XHG=750 XHG=817 XHG=991 XHG=1171 YBD=889 YBD=880 YBD=888 YBD=880 YBD=881 YHG=852>deficiency, YHG=852>and YHG=851>would YHG=852>better YHG=858>account YHG=851>for YHG=861>a YHG=851>genetic YHG=851>incidence YHG=852>of " XBD=2433 XBD=1488 XBD=1607 XBD=1670 XBD=1735 XBD=1789 XBD=1937 XBD=2028 XBD=2212 XBD=2339 XHG=1304 XHG=1503 XHG=1622 XHG=1684 XHG=1750 XHG=1804 XHG=1952 XHG=2042 XHG=2226 XHG=2353 YBD=891 YBD=890 YBD=882 YBD=884 YBD=883 YHG=853>Equivalent YHG=853>values YHG=853>for YHG=853>the YHG=854>83 YHG=854>patients YHG=853>with YHG=859>cutaneous YHG=853>lesions YHG=863>were " XBD=1208 XBD=328 XBD=564 XBD=607 XBD=669 XBD=771 XBD=890 XBD=975 XBD=1091 XBD=1161 XHG=94 XHG=339 XHG=574 XHG=618 XHG=681 XHG=783 XHG=986 XHG=1101 XHG=1171 YBD=933 YBD=924 YBD=933 YBD=925 YBD=924 YBD=933 YBD=925 YHG=896>meningococcal YHG=895>susceptibility YHG=895>in YHG=896>the YHG=896>Heist YHG=896>family YHG=895>than YHG=896>would YHG=905>any YHG=896>of XBD=1395XHG=900 XBD=1507 XBD=1588 XBD=1677 XBD=1909 XBD=2009 XBD=2220 XBD=2292 XBD=2344 XBD=2432 XHG=1304 XHG=1419 XHG=1527 XHG=1607 XHG=1698 XHG=1930 XHG=2028 XHG=2239 XHG=2311 XHG=2363 YBD=934 YBD=936 YBD=935 YBD=927 YBD=928 YHG=899>37 9, YHG=899>11 YHG=898>and YHG=899>3’ YHG=898>respectively. YHG=898>This YHG=898>progressive YHG=898>fall YHG=899>in YHG=898>titre · 0, " XBD=139 XBD=356 XBD=579 XBD=703 XBD=755 XBD=819 XBD=915 XBD=1012 XBD=1201 XHG=93 XHG=156 XHG=375 XHG=600 XHG=722 XHG=774 XHG=839 XHG=933 XHG=1031 YBD=970 YBD=977 YBD=974 YBD=969 YBD=970 YBD=970 YHG=941>the YHG=940>complement YHG=940>deficiencies, YHG=940>which YHG=950>so YHG=940>far YHG=941>have YHG=941>been YHG=941>autosomal |>" XBD=1443 XBD=1521 XBD=1696 XBD=1762 XBD=1836 XBD=1986 XBD=2049 XBD=2160 XBD=2204 XBD=2232 XBD=2354 XBD=2395 XBD=2432 XBD=1941 XHG=1303 XHG=1455 XHG=1533 XHG=1708 XHG=1775 XHG=1952 XHG=1997 XHG=2061 XHG=2172 XHG=2216 XHG=2243 XHG=2368 XHG=2407 XHG=1848 YBD=980 YBD=971 YBD=972 YBD=972 YHG=949>suggests YHG=943>that YHG=949>treatment YHG=943>has YHG=942>this YHG=943>in YHG=942>the YHG=951>group YHG=953>as YHG=952>a YHG=943>whole. YHG=943>It YHG=943>is YHG=943>effect



" YBD=1014 YHG=985>recessive. " XBD=238 XBD=1448XHG=93 XBD=1492 XBD=1556 XBD=1691 XBD=1735 XBD=1912 XBD=1956 XBD=2101 XBD=2177 XBD=2323 XBD=2368 XBD=2432 XHG=1303 XHG=1460 XHG=1505 XHG=1568 XHG=1703 XHG=1747 XHG=1924 XHG=1968 XHG=2113 XHG=2189 XHG=2336 XHG=2380 YBD=1015 YBD=1024 YBD=1016 YBD=1017 YHG=987>different YHG=993>to YHG=987>finding YHG=987>Colombia YHG=987>in YHG=987>patients YHG=987>also YHG=988>resident YHG=988>in YHG=987>the

" XBD=1046 XBD=1202 XBD=174 XBD=268 XBD=300 XBD=425 XBD=623 XBD=787 XBD=956 XHG=123 XHG=184 XHG=285 XHG=312 XHG=436 XHG=636 XHG=970 XHG=1058 YBD=1057 YBD=1058 YBD=1065 YBD=1066 YBD=1058 YBD=1066 YHG=1029>We YHG=1021>usedl YHG=1038>a YHG=1029>second YHG=1028>fluorescent YHG=1029>anti-IgM YHG=1028>antibody, YHG=1028>after YHG=1029>allowing XBD=1517XHG=799 XBD=1602 XBD=1694 XBD=1774 XBD=1876 XBD=1917 XBD=2072 XBD=2297 XBD=2432 XHG=2306 XHG=1303 XHG=1526 XHG=1615 XHG=1704 XHG=1783 XHG=1885 XHG=1927 XHG=2082 YBD=1069 YBD=1060 YBD=1061 YHG=1041>area. YHG=1032>This YHG=1041>may YHG=1032>relate YHG=1038>to YHG=1031>different YHG=1031>transmission YHG=1031>indexes " " " " " " " " " " "

XBD=138 XHG=911 XBD=372 XBD=448 XBD=520 XBD=666 XBD=729 XBD=858 XBD=901 XBD=949 XBD=1096 XBD=1138 XBD=1201 XHG=93 XHG=149 XHG=384 XHG=459 XHG=530 XHG=676 XHG=740 XHG=869 XHG=961 XHG=1106 XHG=1149 YBD=1104 YBD=1110 YBD=1109 YBD=1102 YBD=1110 YBD=1102 YHG=1074>the YHG=1073>meningococci YHG=1073>that YHG=1073>had YHG=1073>infected YHG=1073>the YHG=1073>patient YHG=1080>to YHG=1073>be YHG=1073>exposed YHG=1080>to YHG=1073>the XBD=1596 XBD=1350 XBD=1432 XBD=1506 XHG=1303 XHG=1363 XHG=1444 XHG=1518 YBD=1104 YBD=1113 YHG=1075>for YHG=1075>Lbb YHG=1076>and YHG=1076>Lbp. XBD=186 XHG=840 XBD=238 XBD=311 XBD=455 XBD=536 XBD=670 XBD=752 XBD=822 XBD=973 XBD=1051 XBD=1110 XBD=1202 XHG=93 XHG=202 XHG=249 XHG=330 XHG=475 XHG=553 XHG=687 XHG=769 XHG=991 XHG=1069 XHG=1127 YBD=1147 YBD=1145 YBD=1146 YBD=1147 YBD=1154 YBD=1146 YBD=1146 YBD=1153 YHG=1127>serum YHG=1117>of YHG=1117>patient, YHG=1118>and YHG=1117>proved YHG=1117>that YHG=1117>the YHG=1117>patients YHG=1117>had YHG=1127>no YHG=1117>IgM XBD=250 XHG=817 XBD=375 XBD=464 XBD=715 XBD=806 XBD=902 XBD=1038 XBD=1200 XHG=93 XHG=260 XHG=385 XHG=474 XHG=728 XHG=912 XHG=1048 YBD=1191 YBD=1190 YBD=1198 YBD=1191 YBD=1198 YBD=1191 YHG=1161>antibodies YHG=1161>against YHG=1161>their YHG=1162>meningococci. YHG=1162>This YHG=1171>more YHG=1161>specific YHG=1161>immunoXBD=250 XHG=861 XBD=320 XBD=422 XBD=519 XBD=639 XBD=690 XBD=842 XBD=932 XBD=1028 XBD=1062 XBD=1201 XHG=92 XHG=267 XHG=340 XHG=441 XHG=539 XHG=657 XHG=709 XHG=951 XHG=1047 XHG=1082 YBD=1243 YBD=1234 YBD=1242 YBD=1235 YBD=1235 YBD=1234 YBD=1235 YHG=1205>deficiency YHG=1206>has YHG=1206>since YHG=1206>been YHG=1206>found YHG=1206>in YHG=1206>patients YHG=1207>who YHG=1206>have YHG=1215>a YHG=1206>normal XBD=185 XHG=850 XBD=273 XBD=325 XBD=416 XBD=495 XBD=682 XBD=836 XBD=865 XBD=1059 XBD=1155 XBD=1207 XHG=92 XHG=199 XHG=288 XHG=334 XHG=433 XHG=509 XHG=697 XHG=880 XHG=1074 XHG=1169 YBD=1280 YBD=1278 YBD=1286 YBD=1287 YBD=1279 YBD=1279 YBD=1279 YHG=1259>serum YHG=1250>level YHG=1250>of YHG=1249>IgM, YHG=1250>and YHG=1257>represents YHG=1250>possibly YHG=1260>a YHG=1259>commoner YHG=1249>form YHG=1250>of XBD=200 XHG=541 XBD=459 XBD=516 XBD=790 XBD=1003 XBD=1199 XHG=92 XHG=223 XHG=484 XHG=816 XHG=1030 YBD=1331 YBD=1323 YBD=1331 YBD=1331 YBD=1332 YHG=1294>genetic YHG=1294>predisposition YHG=1301>to YHG=1294>meningococcal YHG=1295>meningitis. YHG=1294>Certainly, XBD=159 XHG=958 XBD=189 XBD=256 XBD=337 XBD=515 XBD=573 XBD=677 XBD=865 XBD=948 XBD=982 XBD=1200 XHG=92 XHG=168 XHG=198 XHG=264 XHG=345 XHG=523 XHG=582 XHG=686 XHG=874 XHG=991 YBD=1367 YBD=1374 YBD=1376 YBD=1367 YBD=1368 YBD=1376 YHG=1339>both YHG=1338>it YHG=1338>and YHG=1338>IgM YHG=1338>deficiency YHG=1348>are YHG=1339>much YHG=1347>commoner YHG=1339>than YHG=1339>is YHG=1339>complement XBD=249 XHG=673 XBD=288 XBD=353 XBD=550 XBD=663 XBD=842 XBD=1021 XBD=1127 XBD=1200 XHG=92 XHG=257 XHG=296 XHG=361 XHG=561 XHG=850 XHG=1029 XHG=1136 YBD=1420 YBD=1410 YBD=1419 YBD=1411 YBD=1420 YBD=1420 YBD=1419 YBD=1412 YHG=1382>deficiency YHG=1383>in YHG=1391>our YHG=1383>experience. YHG=1383>While YHG=1383>properdin YHG=1383>deficiency YHG=1383>might YHG=1383>also XBD=202 XHG=847 XBD=263 XBD=490 XBD=582 XBD=725 XBD=762 XBD=835 XBD=899 XBD=1138 XBD=1198 XHG=92 XHG=214 XHG=275 XHG=503 XHG=594 XHG=739 XHG=773 XHG=911 XHG=1151 YBD=1463 YBD=1455 YBD=1463 YBD=1464 YBD=1456 YBD=1457 YBD=1456 YHG=1427>explain YHG=1426>the YHG=1427>predominant YHG=1427>male YHG=1433>pattern, YHG=1427>it YHG=1436>was YHG=1427>the YHG=1428>heat-sensitive YHG=1427>C3 XBD=264 XHG=815 XBD=339 XBD=411 XBD=495 XBD=538 XBD=600 XBD=686 XBD=804 XBD=853 XBD=1089 XBD=1132 XBD=1199 XHG=91 XHG=275 XHG=350 XHG=422 XHG=506 XHG=548 XHG=612 XHG=696 XHG=857 XHG=1100 XHG=1143 YBD=1508 YBD=1509 YBD=1508 YBD=1500 YBD=1508 YBD=1500 YBD=1501 YHG=1477>component YHG=1470>that YHG=1480>was YHG=1471>vital YHG=1478>to YHG=1471>the YHG=1471>IgM YHG=1471>killing YHG=1471>of YHG=1472>meningococci YHG=1472>in YHG=1481>our XBD=205 XHG=844 XBD=280 XBD=370 XBD=593 XBD=739 XBD=828 XBD=980 XBD=1047 XBD=1199 XHG=92 XHG=222 XHG=296 XHG=385 XHG=610 XHG=755 XHG=995 XHG=1063 YBD=1550 YBD=1544 YBD=1552 YBD=1544 YBD=1545 YHG=1516>studies, YHG=1515>and YHG=1515>IgM YHG=1515>complement YHG=1516>fixation YHG=1525>goes YHG=1516>through YHG=1515>the YHG=1516>classical

" XBD=228 XHG=91 YBD=1596 YHG=1560>pathway.

" " " " "


Leishmaniasis Laboratory, University of Brasília, Brasília, Brazil

Walderrama L, Santrich C, Saravia NG. Recurrence of tegumentary leishmaniasis. Lancet 1985; ii: 557-58. 2. Llanos-Cuentas EA, Marsden PD, Lago EL, Barreto AC, Cuba CC, Johnson WD. Human mucocutaneous leishmaniasis in Três Bracos, Bahia-Brazil. An area of Leishmania braziliensis braziliensis transmission II: Cutaneous disease: presentation and evolution Revta Soc Bras Med Trop 1984; 17: 169-77. 3. Marsden PD, Llanos-Cuentas EA, Lago EL, et al. Human mucocutaneous leishmaniasis in Três Bracos, Bahia-Brazil: An area of Leishmania braziliensis braziliensis transmission III: Mucosal disease: presentation and initial evolution. Revta Soc Bras Med Trop 1984; 17: 179-86. 4. Cuba CAC, Marsden PD, Barreto AC, Rocha R, Sampaio RN, Patzlaff L. Parasitological and immunological diagnosis of American (mucocutaneous) leishmaniasis. Bull PAHO 1981; 15: 249-59. 5. Cuba CAC, Llanos-Cuentas EA, Barreto AC, et al. Human mucocutaneous leishmaniasis in Três Bracos, Bahia, Brazil. An area of Leishmania braziliensis braziliensis transmission. I: Laboratory diagnosis. Revta Soc Bras Med Trop 1984; 17: 161-67. 6. Walton BC. Evaluation of chemotherapy of American leishmaniasis by the indirect fluorescent antibody test. Am J Trop Med Hyg 1980; 29: 747-52. 1.

Weigle KA,

XBD=1198XHG=808 XBD=156 XBD=229 XBD=313 XBD=372 XBD=484 XBD=536 XBD=612 XBD=796 XBD=841 XBD=1085 XBD=1129 XHG=119 XHG=168 XHG=242 XHG=326 XHG=385 XHG=496 XHG=549 XHG=624 XHG=853YBD=1633 XHG=1097 XHG=1142 YBD=1632 YBD=1640 YBD=1641 YBD=1633 YHG=1604>At YHG=1604>that YHG=1604>time YHG=1613>we YHG=1603>found YHG=1613>no YHG=1604>IgA YHG=1604>antibodies YHG=1611>to YHG=1604>meningococci YHG=1604>in YHG=1614>our XBD=212 XHG=851 XBD=271 XBD=328 XBD=441 XBD=612 XBD=826 XBD=903 XBD=1109 XBD=1200 XHG=92 XHG=238 XHG=295 XHG=354 XHG=466 XHG=640 XHG=929 XHG=1135 YBD=1685 YBD=1678 YBD=1683 YBD=1685 YBD=1677 YBD=1685 YBD=1677 YHG=1648>patients YHG=1657>or YHG=1648>in YHG=1649>other YHG=1649>controls, YHG=1648>supporting YHG=1648>the YHG=1648>hypothesis YHG=1648>that XBD=306 XHG=903 XBD=375 XBD=516 XBD=613 XBD=678 XBD=817 XBD=891 XBD=974 XBD=1088 XBD=1133 XBD=1197 XHG=90 XHG=319 XHG=389 XHG=529 XHG=626 XHG=692 XHG=831 XHG=987 XHG=1101 XHG=1145 YBD=1729 YBD=1730 YBD=1722 YBD=1721 YBD=1729 YBD=1721 YBD=1721 YHG=1692>meningococci YHG=1701>can YHG=1692>directly YHG=1702>cross YHG=1693>the YHG=1701>mucosa YHG=1693>and YHG=1693>gain YHG=1702>access YHG=1699>to YHG=1692>the XBD=235 XHG=966 XBD=387 XBD=457 XBD=652 XBD=762 XBD=947 XBD=995 XBD=1093 XBD=1137 XBD=1197 XHG=89 XHG=253 XHG=406 XHG=477 XHG=671 XHG=783 XHG=1008 XHG=1112 XHG=1156 YBD=1772 YBD=1766 YBD=1773 YBD=1775 YBD=1765 YBD=1765 YBD=1766 YHG=1737>meninges YHG=1736>through YHG=1737>the YHG=1737>cribriform YHG=1737>plate, YHG=1737>especially YHG=1736>if YHG=1736>there YHG=1737>is YHG=1746>no XBD=231 XHG=587 XBD=323 XBD=407 XBD=567 XBD=903 XBD=1048 XBD=1100 XBD=1199 XHG=91 XHG=251 XHG=343 XHG=427 XHG=924 XHG=1068 XHG=1120 YBD=1816 YBD=1815 YBD=1808 YBD=1814 YBD=1817 YBD=1808 YBD=1809 YHG=1786>secretory YHG=1779>IgM YHG=1779>that YHG=1779>contains YHG=1778>antimeningococcal YHG=1779>activity YHG=1786>to YHG=1786>meet

" XBD=172 XHG=89 YBD=1854 YHG=1825>them. Department of Chemical Immunology, Charing Cross and Westminster Medical School, Westminster Hospital, London SW1P 2AR


1 Hobbs JR, Milner RDG, Watt PJ. Gamma-M deficiency predisposing J iv: 583-86. meningococcal septicaemia. Br Med 1967; 2 Hobbs JR. IgM deficiency. Birth Defects, Orig Art Ser 1975; 11: 112-16.



" XBD=2425 XBD=1481RECURRENCE XBD=1596 XBD=1670 XBD=1854 XBD=1952 XBD=1994 XBD=2029 XBD=2136 XBD=2286 XBD=2318 XHG=1332 YBD=2263 XHG=1495 XHG=1609 XHG=1682 XHG=1867 XHG=1965 XHG=2009 XHG=2045 XHG=2148 XHG=2299 XHG=2329 YBD=2264 YBD=2270 YBD=2269 YBD=2271 YBD=2268 YHG=2234>SIR,-Dr YHG=2235>Wood YHG=2234>and YHG=2234>colleagues YHG=2234>(Nov YHG=2235>2, YHG=2243>p YHG=2234>1008) YHG=2234>describe YHG=2243>a, YHG=2243>reverOF SOUTH AMERICAN " XBD=2427 XBD=1373 XHG=2385 XBD=1558 XBD=1612 XBD=1820 XBD=1993 XBD=2077 XBD=2209 XBD=2366 XHG=1297 XHG=1392 XHG=1580 XHG=1635 XHG=1842 XHG=2015 XHG=2096 XHG=2230 YBD=2308 YBD=2316 YBD=2307 YBD=2315 YHG=2279>sible YHG=2279>reduction YHG=2279>in YHG=2278>glomerular YHG=2278>filtration YHG=2284>rate YHG=2278>(GFR) YHG=2278>induced YHG=2278>by LEISHMANIASIS TEGUMENTARY " XBD=2425 XBD=1449 XHG=2370 XBD=1498 XBD=1566 XBD=1745 XBD=1800 XBD=1918 XBD=1994 XBD=2042 XBD=2180 XBD=2351 XHG=1296 YBD=2351 XHG=1465 XHG=1514 XHG=1582 XHG=1762 XHG=1810 XHG=1935 XHG=2011 XHG=2059 XHG=2196 YBD=2360 YHG=2322>We YBD=2359 YBD=2352 YHG=2323>captopril YHG=2323>in YHG=2323>the YHG=2328>treatment YHG=2322>of YHG=2323>ascites YHG=2323>due YHG=2329>to YHG=2322>hepatic YHG=2322>cirrhosis. XBD=284 XHG=847 XBD=490 XBD=580 XBD=640 XBD=773 XBD=825 XBD=885 XBD=1090 XBD=1148 XBD=1201 XHG=122 XHG=305 XHG=511 XHG=602 XHG=656 XHG=796 XHG=913YBD=2393 XHG=1111 XHG=1169 YBD=2399 YBD=2394 YBD=2400 YBD=2394 YBD=2393YHG=2357>all YHG=2365>SIR,-The YHG=2364>Colombian YHG=2365>data YHG=2364>of YHG=2364>Weigle YHG=2371>et YHG=2364>stimulated YHG=2374>us YHG=2370>to " XBD=1648 XBD=1401 XBD=1430 XBD=1558 XHG=1297 XHG=1414 XHG=1443 XHG=1571 YBD=2404 YBD=2395 YBD=2396 YHG=2374>report YHG=2377>a YHG=2366>similar YHG=2376>case. |>"XBD=2426 XBD=202 XBD=268 XBD=477 XBD=529 XBD=698 XBD=932 XBD=976 XBD=1065 XBD=1199 XHG=91 XHG=213 XHG=278 XHG=488 XHG=540 XHG=710 XHG=944 XHG=987 XHG=1076 YBD=2446 YBD=2437 YBD=2438 YBD=2436 YBD=2437 YBD=2448 YHG=2409>analyse YHG=2418>our YHG=2408>information YHG=2418>on YHG=2415>recurrent YHG=2408>leishmaniasis YHG=2409>in YHG=2409>Tres YHG=2408>Brazos, " XBD=1358 XBD=1560 XBD=1693 XBD=1782 XBD=1965 XBD=2063 XBD=2191 XBD=2264 XHG=1330 XHG=1370 XHG=1571 XHG=1705 XHG=1794 XHG=1977 XHG=2075 XHG=2203 XHG=2277 YBD=2439 YBD=2449 YBD=2440 YBD=2442 YHG=2411>A YHG=2411>65-year-old YHG=2419>woman YHG=2411>with YHG=2411>rheumatic YHG=2411>heart YHG=2411>disease YHG=2421>was YHG=2411>admitted XBD=186 XHG=959 XBD=313 XBD=435 XBD=528 XBD=587 XBD=816 XBD=860 XBD=939 XBD=990 XBD=1200 XHG=90 XHG=207 XHG=334 XHG=455 XHG=550 XHG=601 XHG=835 XHG=879 XHG=1008 YBD=2488 YBD=2487 YBD=2482 YBD=2481 YBD=2481 YHG=2453>Bahia, YHG=2453>Brazil, YHG=2453>where YHG=2453>95% YHG=2453>of YHG=2452>transmission YHG=2453>is YHG=2453>due YHG=2459>to YHG=2452>Leishmania " XBD=2427 XBD=1328 XBD=1519 XBD=1653 XBD=1777 XBD=1907 XBD=1951 XBD=2067 XBD=2166 XBD=2351 XHG=1296 XHG=1343 XHG=1535 XHG=1668 XHG=1791 XHG=1923 XHG=1965 XHG=2081 XHG=2181 XHG=2365 YBD=2483 YBD=2492 YBD=2484 YHG=2455>in YHG=2456>congestive YHG=2455>cardiac YHG=2454>failure YHG=2454>(CCF). YHG=2455>A YHG=2455>mitral YHG=2455>valve YHG=2455>prosthesis YHG=2456>had " XBD=1200 XBD=257 XBD=449 XBD=568 XBD=700 XBD=819 XBD=1028 XHG=92 XHG=272 XHG=461 XHG=584 XHG=833 XHG=1042 YBD=2527 YBD=2535 YBD=2526 YBD=2526 YBD=2533 YHG=2497>braziliensis YHG=2497>braziliensis YHG=2491>(Lbb)2 YHG=2497>(table). YHG=2497>These YHG=2506>recurrences YHG=2503>represent XBD=1374XHG=716 XBD=1529 XBD=1579 XBD=1689 XBD=1766 XBD=1871 XBD=1951 XBD=2047 XBD=2108 XBD=2288 XBD=2340 XBD=2424 XHG=1295 XHG=1394 XHG=1547 XHG=1602 XHG=1710 XHG=1786 XHG=1891 XHG=1968 XHG=2067 XHG=2127 XHG=2308 XHG=2359 YBD=2527 YBD=2529 YBD=2528 YBD=2537 YHG=2500>inserted YHG=2499>in YHG=2500>1979, YHG=2499>but YHG=2499>there YHG=2499>had YHG=2500>been YHG=2509>no YHG=2500>reduction YHG=2500>in YHG=2500>pulXBD=212 XBD=292 XBD=380 XBD=501 XBD=634 XBD=770 XBD=858 XBD=1059 XBD=1198 XHG=90 XHG=224 XHG=303 XHG=393 XHG=512 XHG=647 XHG=781 XHG=870 XHG=1071 YBD=2578 YBD=2578 YBD=2570 YBD=2578 YBD=2577 YHG=2542>patients YHG=2541>who YHG=2541>have YHG=2541>shown YHG=2541>clinical YHG=2541>healing YHG=2541>with YHG=2541>subsequent YHG=2541>relapse, |>" " XBD=1425 XBD=1708 XBD=1790 XBD=1865 XBD=1948 XBD=2047 XBD=2217 XBD=2269 XBD=2425 XBD=1546 XHG=1295 XHG=1566 XHG=1729 XHG=1811 XHG=1887 XHG=1968 XHG=2068 XHG=2238 XHG=2291 XHG=1438 YBD=2580 YBD=2572 YBD=2575 YBD=2573 YBD=2581 YBD=2581 YHG=2552>monary YHG=2552>pressure YHG=2543>and YHG=2543>she YHG=2543>had YHG=2544>been YHG=2544>admitted YHG=2551>to YHG=2544>hospital YHG=2550>artery XBD=137 XHG=783 XBD=233 XBD=376 XBD=458 XBD=511 XBD=578 XBD=727 XBD=771 XBD=946 XBD=1035 XBD=1199 XHG=90 XHG=149 XHG=245 XHG=388 XHG=472 XHG=524 XHG=591 XHG=739 XHG=958 XHG=1046 YBD=2615 YBD=2622 YBD=2614 YBD=2615 YBD=2614 YBD=2622 YHG=2592>not YHG=2585>those YHG=2585>patients YHG=2585>who YHG=2586>do YHG=2592>not YHG=2586>respond YHG=2592>to YHG=2591>treatment YHG=2585>with YHG=2585>complete 25 " XBD=2424 XBD=1411 XBD=1513 XBD=1685 XBD=1861 XBD=1922 XBD=2028 XBD=2258 XBD=2324 XHG=1295 XHG=1424 XHG=1527 XHG=1697 XHG=1875 XHG=1936 XHG=2043 XHG=2272 XHG=2336 YBD=2616 YBD=2625 YBD=2624 YBD=2617 YHG=2588>several YHG=2588>times YHG=2587>requiring YHG=2594>treatment YHG=2587>for YHG=2588>CCF. YHG=2588>Captopril YHG=2597>mg YHG=2588>twice " XBD=210 YBD=2666 YHG=2629>healing. XBD=1377XHG=89 XBD=1448 XBD=1560 XBD=1602 XBD=1802 XBD=1921 XBD=1999 XBD=2180 XBD=2354 XBD=2425 XHG=1295 XHG=1387 XHG=1460 XHG=1570 XHG=1613 XHG=1818 XHG=1937 XHG=2009 XHG=2192 XHG=2364 YBD=2669 YBD=2660 YBD=2666 YBD=2667 YBD=2661 YBD=2670 YBD=2668 YBD=2662 YHG=2631>daily YHG=2641>was YHG=2632>added YHG=2632>in YHG=2631>November, YHG=2625>1984,1 YHG=2632>and YHG=2639>symptoms YHG=2632>improved YHG=2633>and XBD=152 XHG=726 XBD=215 XBD=381 XBD=427 XBD=490 XBD=632 XBD=718 XBD=843 XBD=1019 XBD=1142 XBD=1199 XHG=119 XHG=161 XHG=223 XHG=391 XHG=433 XHG=499 XHG=641 XHG=852YBD=2703 XHG=1029 XHG=1151 YBD=2711 YBD=2710 YBD=2702 YBD=2703 YBD=2703 YBD=2702 YHG=2675>In YHG=2683>our YHG=2673>follow-up YHG=2673>of YHG=2674>146 YHG=2674>patients YHG=2673>with YHG=2674>treated YHG=2680>cutaneous YHG=2674>lesions YHG=2673>for " XBD=2424 XBD=1380 XBD=1465 XBD=1530 XBD=1772 XBD=1828 XBD=1935 XBD=2110 XBD=2196 XBD=2280 XHG=1294 XHG=1404 XHG=1489 XHG=1554 XHG=1796 XHG=1852 XHG=1958 XHG=2136 XHG=2219 XHG=2304 YBD=2707 YBD=2712 YBD=2704 YBD=2705 YHG=2676>there YHG=2685>was YHG=2685>no YHG=2676>deterioration YHG=2676>in YHG=2676>renal YHG=2676>function. YHG=2675>She YHG=2686>was YHG=2676>further XBD=102 XHG=907 XBD=198 XBD=247 XBD=312 XBD=409 XBD=475 XBD=629 XBD=674 XBD=738 XBD=820 XBD=894 XBD=959 XBD=1155 XBD=1199 XHG=88 XHG=115 XHG=210 XHG=253 XHG=325 XHG=423 XHG=489 XHG=641 XHG=686 XHG=751 XHG=833 XHG=973 XHG=1167 YBD=2747 YBD=2755 YBD=2754 YBD=2746 YBD=2747 YBD=2755 YHG=2727>a YHG=2727>mean YHG=2717>of YHG=2724>two YHG=2727>years YHG=2719>7% YHG=2717>relapsed YHG=2718>in YHG=2718>the YHG=2718>skin YHG=2718>and YHG=2719>3% YHG=2718>progressed YHG=2724>to " XBD=2422 XBD=1444 XBD=1486 XBD=1614 XBD=1733 XBD=1914 XBD=2044 XBD=2171 XBD=2335 XHG=1294 XHG=1453 XHG=1496 XHG=1625 XHG=1743 XHG=1924 XHG=2054 XHG=2182 XHG=2346 YBD=2747 YBD=2749 YBD=2756 YBD=2757 YHG=2720>admitted YHG=2720>in YHG=2720>cardiac YHG=2720>failure YHG=2720>(increased YHG=2720>jugular YHG=2729>venous YHG=2729>pressure, YHG=2720>periHowever, " XBD=1199 XBD=214 XBD=370 XBD=666 XBD=721 XBD=818 XBD=969 XBD=1066 XHG=88 XHG=232 XHG=573 XHG=683 XHG=732 XHG=986 XHG=1083 YBD=2791 YBD=2791 YBD=2799 YBD=2791 YBD=2791 YHG=2762>mucosal YHG=2755>disease.2 YHG=2771>many YHG=2762>of YHG=2762>these YHG=2762>patients YHG=2771>were YHG=2762>treated XBD=1401XHG=837 XBD=1551 XBD=1810 XBD=1887 XBD=2019 XBD=2061 XBD=2090 XBD=2177 XBD=2281 XBD=2349 XBD=2422 XHG=1294 XHG=1414 XHG=1566 XHG=1826 XHG=1899 XHG=2032 XHG=2074 XHG=2104 XHG=2190 XHG=2295 XHG=2361 YBD=2798 YBD=2801 YBD=2792 YBD=2793 YHG=2764>pheral YHG=2764>oedema, YHG=2764>hepatomegaly, YHG=2765>and YHG=2764>ascites) YHG=2770>at YHG=2773>a YHG=2764>time YHG=2763>when YHG=2764>she YHG=2773>was XBD=156 XHG=748 XBD=245 XBD=508 XBD=611 XBD=699 XBD=739 XBD=940 XBD=1011 XBD=1081 XBD=1198 XHG=87 XHG=163 XHG=254 XHG=517 XHG=621 XHG=708 XHG=951 XHG=1019 XHG=1090 YBD=2835 YBD=2842 YBD=2835 YBD=2836 YBD=2834 YBD=2835 YHG=2807>with YHG=2806>weak YHG=2806>antileishmanial YHG=2806>drugs YHG=2806>such YHG=2816>as YHG=2806>nifurtimox. YHG=2806>For YHG=2806>this YHG=2815>reason " XBD=2421 XBD=1399 XBD=1590 XBD=1757 XBD=1809 XBD=1877 XBD=1978 XBD=2082 XBD=2233 XHG=1294 XHG=1412 XHG=1605 XHG=1771 XHG=1824 XHG=1889 XHG=1991 XHG=2097 XHG=2248 YBD=2843 YBD=2842 YBD=2836 YBD=2837 YBD=2844 YBD=2845 YHG=2808>taking YHG=2808>frusemide, YHG=2808>captopril YHG=2809>25 YHG=2817>mg YHG=2809>twice YHG=2807>daily, YHG=2808>digoxin, YHG=2808>thyroxine, " XBD=2423 XBD=160 XHG=846 XBD=178 XBD=263 XBD=410 XBD=554 XBD=684 XBD=770 XBD=834 XBD=926 XBD=1033 XBD=1133 XBD=1198 XBD=1471 XBD=1550 XBD=1717 XBD=1992 XBD=2069 XBD=2269 XBD=2355 XHG=88 XHG=169 XHG=192 XHG=273 XHG=422 XHG=566 XHG=694 XHG=781 XHG=937 XHG=1045 XHG=1146 XHG=1294 XHG=1488 XHG=1565 XHG=1735 XHG=2008 XHG=2085 XHG=2282 XHG=2371 YBD=2879 YBD=2877 YBD=2888 YBD=2887 YBD=2883 YBD=2879 YBD=2880 YBD=2880 YBD=2879 YBD=2886 YBD=2881 YBD=2887 YBD=2888 YHG=2850>table YHG=2857>i YHG=2850>only YHG=2850>includes YHG=2850>patients YHG=2851>treated YHG=2851>with YHG=2850>the YHG=2857>most YHG=2850>active YHG=2851>drug, YHG=2850>the YHG=2852>mianserin, YHG=2852>and YHG=2851>warfarin. YHG=2852>Spironolactone YHG=2861>was YHG=2852>introduced YHG=2852>(100 YHG=2861>mg XBD=271 XHG=476 XBD=462 XBD=671 XHG=88 XHG=284 YBD=2930 YBD=2924 YBD=2931 YHG=2894>pentavalent YHG=2894>antimonial YHG=2894>glucantime. " XBD=2423 XBD=1382 XBD=1484 XBD=1556 XBD=1616 XBD=1793 XBD=1876 XBD=1947 XBD=2120 XBD=2204 XBD=2251 XBD=2292 XBD=2361 XHG=1293 XHG=1392 XHG=1494 XHG=1564 XHG=1624 XHG=1803 XHG=1885 XHG=1956 XHG=2122 XHG=2212 XHG=2260 XHG=2305 XHG=2371 YBD=2933 YBD=2925 YBD=2924 YBD=2932 YHG=2896>twice YHG=2896>daily) YHG=2896>and YHG=2896>the YHG=2896>frusemide YHG=2896>dose YHG=2906>was YHG=2883>increased YHG=2895>from YHG=2897>80 YHG=2902>to YHG=2896>120 YHG=2905>mg XBD=270 XHG=907 XBD=348 XBD=486 XBD=572 XBD=693 XBD=831 XBD=884 XBD=972 XBD=1144 XBD=1197 XHG=117 XHG=292 XHG=370 XHG=509 XHG=594 XHG=716 XHG=853 XHG=994YBD=2967 XHG=1165 YBD=2974 YBD=2975 YBD=2968 YBD=2967 YBD=2967 YHG=2938>Although YHG=2947>our YHG=2938>relapse YHG=2945>rate YHG=2948>seems YHG=2939>similar YHG=2945>to YHG=2938>that YHG=2939>observed YHG=2939>in " XBD=2421 XBD=1382 XBD=1487 XBD=1555 XBD=1689 XBD=1833 XBD=1909 XBD=2066 XBD=2122 XBD=2209 XBD=2299 XHG=1293 XHG=1397 XHG=1503 XHG=1569 XHG=1703 XHG=1847 XHG=1922 XHG=2085 XHG=2136 XHG=2223 XHG=2312 YBD=2970 YBD=2977 YBD=2969 YBD=2968 YHG=2940>twice YHG=2940>daily. YHG=2940>No YHG=2939>further YHG=2940>diuresis YHG=2950>was YHG=2940>induced. YHG=2941>10 YHG=2940>days YHG=2939>after YHG=2940>admisXBD=240 XHG=888 XBD=301 XBD=385 XBD=602 XBD=683 XBD=742 XBD=863 XBD=957 XBD=1197 XHG=88 XHG=262 XHG=324 XHG=407 XHG=626 XHG=704 XHG=765 XHG=980 YBD=3011 YBD=3019 YBD=3012 YBD=3011 YBD=3019 YHG=2981>Colombia YHG=2991>no YHG=2982>real YHG=2983>comparison YHG=2992>can YHG=2983>be YHG=2983>made. YHG=2982>The YHG=2983>predominant " XBD=2422 XBD=1372 XBD=1435 XBD=1577 XBD=1718 XBD=1929 XBD=2043 XBD=2106 XBD=2132 XBD=2321 XHG=1294 XHG=1383 XHG=1444 XHG=1587 XHG=1727 XHG=1939 XHG=2051 XHG=2115 XHG=2140 XHG=2330 YBD=3018 YBD=3013 YBD=3021 YBD=3012 YHG=2984>sion, YHG=2984>the YHG=2984>thiazide YHG=2984>diuretic YHG=2984>metolazone, YHG=2984>which YHG=2984>has YHG=2994>a YHG=2983>synergistic YHG=2983>effect XBD=208 XHG=773 XBD=257 XBD=325 XBD=409 XBD=464 XBD=640 XBD=756 XBD=947 XBD=1093 XBD=1142 XBD=1197 XHG=87 XHG=226 XHG=274 XHG=343 XHG=427 XHG=477 XHG=657 XHG=965 XHG=1110 XHG=1160 YBD=3061 YBD=3054 YBD=3055 YBD=3056 YBD=3063 YHG=3026>parasite YHG=3026>in YHG=3026>the YHG=3035>area YHG=3026>of YHG=3026>Colombia YHG=3027>under YHG=3027>discussion YHG=3036>appears YHG=3033>to YHG=3027>be " XBD=2423 XBD=1369 XBD=1560 XBD=1637 XBD=1859 XBD=1904 XBD=2025 XBD=2168 XBD=2317 XHG=1293 XHG=1382 XHG=1574 XHG=1650 XHG=1876 XHG=1916 XHG=2038 XHG=2182 XHG=2328 YBD=3062 YBD=3055 YBD=3063 YBD=3057 YBD=3056 YBD=3065 YHG=3028>with YHG=3028>frusemide, YHG=3037>was YHG=3020>introduced YHG=3027>A YHG=3034>potent YHG=3028>diuresis YHG=3027>resulted YHG=3027>(daily .2 " XBD=108 XBD=297 XBD=500 XBD=620 XBD=693 XBD=872 XBD=923 XBD=993 XBD=1198 XHG=86 XHG=127 XHG=310 XHG=516 XHG=640 XHG=711 XHG=891 XHG=941 XHG=1011 YBD=3096 YBD=3098 YBD=3108 YBD=3100 YBD=3106 YBD=3099 YBD=3099 YHG=3069>L YHG=3070>braziliensis YHG=3071>panamensis YHG=3070>(Lbp); YHG=3071>follow-up YHG=3070>in YHG=3070>the YHG=3070>Colombian |>" XBD=1419 XBD=1543 XBD=1593 XBD=1632 XBD=1813 XBD=1887 XBD=1952 XBD=2047 XBD=2171 XBD=2236 XBD=2330 XBD=2394 XBD=2421 XHG=1293 XHG=1430 XHG=1555 XHG=1599 XHG=1718 XHG=1825 XHG=1898 XHG=1963 XHG=2057 XHG=2183 XHG=2248 XHG=2341 XHG=2403 YBD=3107 YBD=3109 YBD=3108 YBD=3100 YBD=3100 YHG=3072>urinary YHG=3078>output YHG=3071>of YHG=3073>2 YHG=3071>litres) YHG=3071>and YHG=3071>her YHG=3072>body YHG=3071>weight YHG=3071>fell YHG=3071>from YHG=3073>67 YHG=3073>7 -XBD=171 XHG=823 XBD=240 XBD=343 XBD=471 XBD=550 XBD=698 XBD=756 XBD=812 XBD=948 XBD=1020 XBD=1069 XBD=1128 XBD=1197 XHG=87 XHG=181 XHG=250 XHG=353 XHG=480 XHG=565 XHG=709 XHG=766 XHG=959 XHG=1029 XHG=1080 XHG=1138 YBD=3141 YBD=3142 YBD=3150 YBD=3143 YBD=3142 YBD=3142 YHG=3113>series YHG=3123>was YHG=3113>much YHG=3114>shorter YHG=3114>(121 YHG=3115>patients YHG=3114>for YHG=3115>six YHG=3114>months YHG=3114>and YHG=3115>44 YHG=3114>for YHG=3123>one " XBD=2236 XBD=1325 XBD=1393 XBD=1694 XBD=1725 XBD=1792 XBD=1866 XBD=2049 XBD=2109 XBD=2139 XHG=1293 XHG=1338 XHG=1496 XHG=1709 XHG=1740 XHG=1804 XHG=1879 XHG=2061 XHG=2123 XHG=2153 YBD=3144 YBD=3143 YBD=3151 YHG=3122>to YHG=3116>64 YHG=3115>Metolazone YHG=3124>mg YHG=3124>was YHG=3115>continued YHG=3115>for YHG=3116>5 YHG=3115>days. XBD=171 XHG=751 XBD=240 XBD=298 XBD=381 XBD=428 XBD=612 XBD=700 XBD=741 XBD=845 XBD=1011 XBD=1057 XBD=1141 XBD=1197 XHG=86 XHG=182 XHG=249 XHG=308 XHG=391 XHG=432 XHG=622 XHG=709 XHG=855 XHG=1019 XHG=1060 XHG=1151 YBD=3193 YBD=3185 YBD=3186 YBD=3187 YBD=3186 YHG=3157>year); YHG=3157>and YHG=3156>the YHG=3157>dose YHG=3157>of YHG=3157>antimonial YHG=3158>used YHG=3158>in YHG=3158>about YHG=3157>one-third YHG=3157>of YHG=3158>what YHG=3167>we " XBD=2421 XBD=1416 XBD=1490 XBD=1645 XBD=1713 XBD=1811 XBD=1864 XBD=1955 XBD=2047 XBD=2156 XBD=2311 XHG=1328 XHG=1429 XHG=1505 XHG=1661 XHG=1727 XHG=1826 XHG=1872 XHG=1967 XHG=2061 XHG=2169 XHG=2329 YBD=3193 YBD=3195 YBD=3186 YBD=3188 YBD=3187 YHG=3159>After YHG=3159>this YHG=3159>diuresis, YHG=3158>the YHG=3159>signs YHG=3158>of YHG=3158>CCF YHG=3168>were YHG=3158>much YHG=3158>reduced. YHG=3158>HowUnlike " XBD=1197 XBD=229 XBD=480 XBD=529 XBD=626 XBD=783 XBD=992 XHG=87 XHG=245 XHG=497 XHG=548 XHG=644 XHG=1011 YBD=3238 YBD=3229 YBD=3230 YBD=3231 YBD=3231 YHG=3200>normally YHG=3202>recommended YHG=3201>in YHG=3202>Tres YHG=3195>Bracos.3 YHG=3201>the YHG=3199>Colombian XBD=1373XHG=940 XBD=1450 XBD=1591 XBD=1811 XBD=1873 XBD=2013 XBD=2191 XBD=2278 XBD=2421 XHG=1293 XHG=1398 XHG=1474 XHG=1615 XHG=1834 XHG=1890 XHG=2038 XHG=2216 XHG=2299 YBD=3239 YBD=3230 YBD=3236 YBD=3237 YBD=3238 YHG=3212>ever, YHG=3202>the YHG=3202>patient YHG=3202>complained YHG=3202>of YHG=3211>nausea, YHG=3202>anorexia, YHG=3203>and YHG=3202>general XBD=256 XHG=767 XBD=315 XBD=410 XBD=499 XBD=581 XBD=629 XBD=750 XBD=913 XBD=1011 XBD=1197 XHG=87 XHG=271 XHG=331 XHG=426 XHG=514 XHG=597 XHG=645 XHG=930 XHG=1026 YBD=3280 YBD=3282 YBD=3273 YBD=3274 YBD=3281 YBD=3274 YHG=3244>experience YHG=3254>we YHG=3254>were YHG=3245>only YHG=3245>able YHG=3252>to YHG=3245>isolate YHG=3246>parasites YHG=3246>from YHG=3246>individual " XBD=2421 XBD=1426 XBD=1518 XBD=1588 XBD=1767 XBD=1807 XBD=1901 XBD=2020 XBD=2152 XBD=2237 XBD=2263 XHG=1293 XHG=1439 XHG=1527 XHG=1598 XHG=1776 XHG=1818 XHG=1910 XHG=2028 XHG=2161 XHG=2247 XHG=2273 YBD=3283 YBD=3274 YBD=3275 YHG=3246>malaise. YHG=3246>This YHG=3255>was YHG=3245>attributed YHG=3253>to YHG=3246>renal YHG=3246>failure YHG=3245>(figure) YHG=3245>with YHG=3255>a YHG=3246>resultant " XBD=2422 XBD=1428 XBD=1485 XBD=1627 XBD=1786 XBD=1999 XBD=2162 XBD=2338 XHG=1293 XHG=1453 XHG=1509 XHG=1650 XHG=1812 XHG=2022 XHG=2185 XHG=2362 YBD=3324 YBD=3318 YBD=3325 YBD=3317 YHG=3290>increase YHG=3289>in YHG=3289>plasma YHG=3289>digoxin. YHG=3289>Interaction YHG=3290>between YHG=3289>captopril YHG=3290>and XBD=164 XHG=790 XBD=212 XBD=380 XBD=452 XBD=599 XBD=727 XBD=779 XBD=925 XBD=1127 XBD=1199 XHG=87 XHG=176 XHG=217 XHG=392 XHG=462 XHG=611 XHG=738 XHG=937 XHG=1138 YBD=3317 YBD=3316 YBD=3325 YBD=3326 YBD=3318 YBD=3318 YHG=3296>cases YHG=3288>of YHG=3295>cutaneous YHG=3290>and YHG=3289>mucosal YHG=3289>relapse YHG=3290>by YHG=3289>hamster YHG=3290>inoculation " XBD=275 XBD=373 XBD=415 XHG=87 XHG=288 XHG=384 YBD=3361 YBD=3360 YBD=3361 YHG=3331>characterise YHG=3332>them YHG=3342>as YHG=3333>Lbb. " XBD=506 XBD=1484XHG=428 XBD=1556 XBD=1740 XBD=1814 XBD=1901 XBD=2005 XBD=2095 XBD=2334 XBD=2422 XHG=1293 XHG=1494 XHG=1567 XHG=1753 XHG=1824 XHG=1911 XHG=2015 XHG=2106 XHG=2346 YBD=3368 YBD=3360 YBD=3366 YBD=3361 YHG=3332>metolazone YHG=3342>was YHG=3332>suspected, YHG=3332>and YHG=3331>both YHG=3332>drugs YHG=3341>were YHG=3332>discontinued, YHG=3332>with " XBD=2420 XBD=1308 XBD=1512 XBD=1633 XBD=1679 XBD=1812 XBD=1911 XBD=2078 XBD=2218 XBD=2283 XHG=1292 XHG=1323 XHG=1527 XHG=1647 XHG=1693 XHG=1827 XHG=1925 XHG=2095 XHG=2231 XHG=2297 YBD=3405 YBD=3412 YBD=3411 YBD=3403 YBD=3404 YHG=3386>a YHG=3377>subsequent YHG=3382>return YHG=3382>to YHG=3376>normal YHG=3375>renal YHG=3375>function. YHG=3375>During YHG=3375>the YHG=3376>metolaXBD=184 XHG=868 XBD=321 XBD=518 XBD=680 XBD=783 XBD=855 XBD=944 XBD=1023 XBD=1198 XHG=118 XHG=196 XHG=334 XHG=532 XHG=691 XHG=796 XHG=957YBD=3404 XHG=1035 YBD=3402 YBD=3403 YBD=3412 YBD=3405 YBD=3412 YHG=3375>The YHG=3375>indirect YHG=3375>fluorescent YHG=3376>antibody YHG=3376>(IFA) YHG=3383>test YHG=3376>with YHG=3376>IgG YHG=3376>conjugate XBD=143 XHG=887 XBD=214 XBD=423 XBD=583 XBD=644 XBD=782 XBD=852 XBD=940 XBD=1130 XBD=1204 XHG=87 XHG=177 XHG=248 XHG=459 XHG=620 XHG=680 XHG=819 XHG=975 XHG=1166 YBD=3446 YBD=3455 YBD=3447 YBD=3448 YBD=3455 YHG=3418>and YHG=3427>an YHG=3419>amastigote YHG=3420>antigen YHG=3419>is YHG=3419>useful YHG=3420>in YHG=3419>the YHG=3420>diagnosis YHG=3419>of " XBD=2422 XBD=1369 XBD=1628 XBD=1690 XBD=1846 XBD=1952 XBD=2104 XBD=2175 XBD=2289 XHG=1292 XHG=1380 XHG=1639 XHG=1701 XHG=1856 XHG=1961 XHG=2114 XHG=2184 XHG=2298 YBD=3455 YBD=3456 YBD=3447 YBD=3448 YHG=3428>zone YHG=3419>administration YHG=3418>the YHG=3419>patient’s YHG=3419>blood YHG=3428>pressure YHG=3419>and YHG=3428>serum YHG=3419>sodium " XBD=1553 XBD=1345 XBD=1419 XHG=1292 XHG=1356 XHG=1432 YBD=3491 YBD=3499 YHG=3463>fell YHG=3464>(see YHG=3462>figure). XBD=336 XHG=895 XBD=606 XBD=674 XBD=722 XBD=820 XBD=861 XBD=886 XBD=953 XBD=1076 XBD=1138 XBD=1197 XHG=87 XHG=347 XHG=618 XHG=684 XHG=731 XHG=830 XHG=870 XHG=963YBD=3491 XHG=1086 XHG=1147 YBD=3493 YBD=3492 YBD=3492 YBD=3492 YBD=3500 YHG=3469>mucocutaneous YHG=3456>leishmaniasis YHG=3464>but YHG=3463>its YHG=3463>value YHG=3473>as YHG=3473>a YHG=3470>test YHG=3463>of YHG=3464>hascure YHG=3469>yet 4,5 ,

5-3 3kg.