ORAL AND MAXILLOFACIAL PATHOLOGY e170 Abstracts left retromolar area. Histological examination was diagnostic for SCC. These cases highlight the importance of monitoring treated patients in order to appropriately treat recurrences.
PE-196 - LOW-GRADE CENTRAL OSTEOSARCOMA IN MANDIBLE: CASE REPORT. RENATA ACAY, WALTER NICCOLI-FILHO, VIVIAN NARANA RIBEIRO EL-ACHKAR, GABRIELA DE MORAIS GOUVÊA LIMA, ESTELA KAMINAGAKURA TANGO, YASMIN RODARTE CARVALHO, ANA LIA ANBINDER. UNESP - UNIVERSIDADE ESTADUAL PAULISTA/SÃO JOSÉ DOS CAMPOS. Low-grade central osteosarcoma of the jaws is an extremely rare lesion that cannot be diagnosed solely through histopathological analysis because microscopically it presents few signs of malignancy. The deﬁnitive diagnosis depends on an evaluation of the clinical course and imaging. A good example of the interdependence among these aspects of diagnostic investigation is presented. Woman, 48, was referred to the oral medicine service due to a mixed radiolucent/radiopaque lesion with aggressive appearance and cortical erosion that affected the body and ramus of the right mandible. An incisional biopsy was performed to investigate the preliminary clinical diagnosis of osteosarcoma. Histologically, the specimen consisted of a proliferation of spindle cells showing very discrete pleomorphism in a ﬁbrous stroma. Irregular and immature osseous trabeculae with evident osteoid production, often surrounded by ﬂat cells, were evident. Combining clinical, radiographic, and histopathological features, the diagnosis was compatible with low-grade central osteosarcoma.
PE-197 - LOW-GRADE MUCOEPIDERMOID CARCINOMA OF MINOR SALIVARY GLAND: CASE REPORT. THAYNÁ MELO DE LIMA MORAIS, AMANDA LAÍSA DE OLIVEIRA LIMA, MATHEUS HENRIQUE ALVES DE LIMA, JÉSSYCA ÍTALA BARROS WANDERLEY DA SILVA, SONIA MARIA SOARES FERREIRA, PABLO AGUSTIN VARGAS, CAMILA MARIA BEDER RIBEIRO. CENTRO UNIVERSITÁRIO CESMAC. Mucoepidermoid carcinoma (MEC) is a malignant glandular epithelial neoplasm. MEC is the most common salivary gland malignancy in both adults and children and demonstrates a wide and uniform age distribution. There is a 3:2 female predilection, but a higher female predominance for tongue and retromolar sites. Half of the tumors occur in the major salivary glands, but the minor salivary glands may also be affected. Most tumors present as ﬁrm, ﬁxed, painless swellings. Dark-skinned young woman, 18, was referred with complains of a “lump.” Intraorally there was a single normochromic node located in the left retromolar region. Biopsy was performed, and histological samples evidenced a low-grade MEC. The patient was referred to a head and neck surgeon to remove the lesion. Currently, the patient has been monitored for 1month with no signs of recurrence. We emphasize the importance of diagnosing malignant minor salivary gland lesions in young patients.
PE-198 - LYMPHANGIOMA IN THE TONGUE: CLINICAL FOLLOW-UP OF 8 YEARS AND IMMUNOHISTOCHEMICAL STAINING WITH D2-40. CLARISSA CASTRO GALVÃO MEDEIROS, JULIANA ANDRADE CARDOSO, FERNANDA GONÇALVES SALUM, KAREN CHERUBINI, MARIA ANTONIA ZANCANARO DE FIGUEIREDO. DIVISION OF ORAL MEDICINE, PUCRS, PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL, BRAZIL.
OOOO February 2014 Lymphangiomas are benign lymphatic malformations that frequently affect the head and neck region. Oral lesions occur mostly in the anterior two thirds of the tongue and produce macroglossia. A lymphangioma in the tongue was clinically followed-up for 8 years. Girl, 3, was referred to the oral medicine unit for assessment of a painless enlargement at the right side of the tongue. A nodule measuring 2.0 1.0 cm was noticed at clinical evaluation. During the ﬁrst 5 years of follow-up there was no enlargement of the lesion, which was conﬁrmed by two ultrasonography exams. After 7 years the nodule increased to 2.5 1.5 cm and the patient reported speech problems due to the lesion growth. Surgery was performed, and the histopathological examination showed several large lymphatic vessels ﬁlled with lymph below the epithelium. Immunostaining with D2-40, a lymphatic vessel-reactive antibody, was positive.
PE-199 - MAJOR SALIVARY GLAND CYSTADENOMA: CASE REPORT. DIANA XAVIER DE BARROS PADILHA, CAMILA MARIA BEDER RIBEIRO, RICARDO VIANA BESSA NOGUEIRA, DARLAN SILVA DE OLIVEIRA, KÁTIA VALÉRIA LIMA DE OLIVEIRA LEITE, SONIA MARIA SOARES FERREIRA, AMANDA LAÍSA DE OLIVEIRA LIMA. CENTRO UNIVERSITÁRIO CESMAC. Cystadenoma is a rare benign epithelial tumor commonly located in minor salivary gland regions that produces smoothsurfaced nodules. There is a female predilection and the most common age is about 57 years. Histopathologically, it is characterized by predominantly multicystic growth with adenomatous proliferation of the epithelium. The epithelial lining is frequently papillary and rarely mucinous. Woman, 58, complained of a slowly growing large painless mass on the left side of her face. Intraoral examination noted a well-deﬁned, homogeneous, smooth-surfaced nodule/mass in the parotid duct region. Pathological cuts revealed benign glandular lesion with multiple small cystic spaces. The lumen contained eosinophilic material with scattered epithelial inﬂammatory cells and cuboidal material lining the epithelium. A diagnosis of major salivary gland cystadenoma was suggested. After 8 months of follow-up, no recurrence was observed and the patient had no major complains.
PE-200 - MALIGNANT TRANSFORMATION OF AN ORAL LICHEN PLANUS IN A 74- YEAR-OLD WOMAN. ANNA TORREZANI, ANA PAULA CANDIDO DOS SANTOS, CAMILA DE BARROS GALLO, ÉRICA PATRÍCIO, NORBERTO NOBUO SUGAYA, FABIO DAUMAS NUNES, CELSO AUGUSTO LEMOS JUNIOR. FACULDADE DE ODONTOLOGIA DA USP. Oral lichen planus (OLP) is a chronic inﬂammatory disease that affects around 1% to 2% of the population. It affects mainly women between ages 30 and 60 years. The most frequently affected anatomical regions in the oral cavity are the buccal mucosa, gingiva, and lateral borders of the tongue, all bilaterally. In about 0.2% of OLP cases, the lesion can transform into a carcinoma, mainly associated with atrophic lesions, erosion, and plaque. Leukodermic woman, 74, had lesions suggestive of OLP for 4 years. OLP was conﬁrmed by histological analysis. After 8 months of follow up, a lesion in the left lingual alveolar ridge was suggestive of carcinoma. Histopathological examination conﬁrmed squamous cell carcinoma. An oncologic surgeon removed the alveolar ridge, mouth ﬂoor, and border of the tongue, which were conﬁrmed by frozen biopsy to be carcinoma. No adjuvant therapy was necessary, and the patient remains free of disease after 3 months.