Manson of schistosoma mansoni

Manson of schistosoma mansoni

114 BOROS ET AL. GASTROENTEROLOGY Vol. 114, No. 1 40. Fujimoto K, Price VH, Granger DN, Specian R, Bergstedt S, Tso P. Effect of ischemia-reperfusi...

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40. Fujimoto K, Price VH, Granger DN, Specian R, Bergstedt S, Tso P. Effect of ischemia-reperfusion on lipid digestion and absorption in rat intestine. Am J Physiol 1991;260:G595–G602. 41. Kubes P, Hunter J, Granger DN. Ischemia/reperfusion-induced feline intestinal dysfunction: importance of granulocyte recruitment. Gastroenterology 1992;103:807–812. 42. Allcock GH, Warner TD, Vane JR. Roles of endothelin receptors in the regional and systemic vascular responses to ET-1 in the anaesthetized ganglion blocked rat: use of selective antagonists. Br J Pharmacol 1995;116:2482–2486. 43. Filep JG, Fo¨ldes-Filep E, Rousseau A, Fournier A, Sirois P, YanoM. Endothelin-1 enhances vascular permeability in the rat heart through the ETA receptor. Eur J Pharmacol 1992;219:343–344.

44. Khimenko PL, Moore TM, Taylor AE. Blocked ETA receptors prevent ischemia and reperfusion injury in rat lungs. J Appl Physiol 1996;80:203–207. Received March 18, 1997. Accepted August 21, 1997. Address requests for reprints to: Konrad Messmer, M.D., Ph.D., Institute for Surgical Research, Ludwig Maximilians University, Klinikum Grosshadern, Marchioninistrasse 15, D-81366 Munich, Germany. Fax: (49) 89-7095-8897. Supported by research grant Biomed 2 Contract No. BMH4-CT95-0875 (DG12-SSMA). Dr. Boros is a Fellow of the Alexander von Humboldt-Foundation from Szent-Gyo ¨rgyi Albert Medical University, Szeged, Hungary.

Manson of Schistosoma mansoni Sir Patrick Manson (1844–1922) was born near Aberdeen, Scotland, the son of an affluent laird and banker. Excessively vigorous exertion in youth left him with a partial paralysis of his right arm. Thereupon he turned to less physically demanding pursuits and chose the study of medicine, first at Aberdeen and later at Edinburgh. Attracted to the Far East, he secured appointment as head of a Baptist Missionary Hospital. Later he settled in Hong Kong where the income from a thriving private practice allowed him to indulge his avocation of investigating exotic diseases. In 1877 he showed that filariasis was transmitted to humans by the mosquito Culex fatigans. In 1890 he moved to London where he was instrumental in founding what became a worldrenowned school of tropical medicine. There he identified the fluke that caused a common form of schistosomiasis. Manson encouraged and advised Ronald Ross in his investigation of the mosquito as a vector of malaria; however, Ross refused to share any credit with Manson when Ross was awarded a Nobel Prize in 1902. A man of great charm and compassion, Sir Patrick retired in 1914 to enjoy his hobbies of fishing and gardening, as well as to ‘‘warm both hands before the fire of life.’’