Morning current oral sessions

Morning current oral sessions

Thursday, December 3, 1998 CONCURRENT ASBMR-IBMS PLENARY Concurrent LECTURES Chairpersons: Jane Aubin Socrates Papapoulos 10:00 am -12:00 P...

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3, 1998







Jane Aubin Socrates Papapoulos

10:00 am -12:00

Plenary Lecture S

830 am - 9:00 am

10:00 am 1097

ECM - Integrin Interactions in Osteoblast Function and Tissue Remodeling Caroline H. Damsky, Ph.D. Professor of Stomatology and Anatomy University of California, San Francisco San Francisco, California, USA

lo:15 am

9:00 am - 9:30 am

Plenary Lecture 6 Supported

by Merck




Bisphosphonates: From the Laboratory to the Clinic and Back Again Graham Russell, M.D., Ph.D. Professor, Human Metabolism & Clinical Biochemistry University of Sheffield Medical School Sheffield, United Kingdom

lo:30 am 1099

Room 302 Chairpersons:

lo:45 am 1100

Nicola Partridge Tatsuo Suds 8:30 am - 9:00 am

Plenary Lecture 7 Genetic Control of Osteoblast Differentiation Gerard Karsenty, M.D. Associate Professor Molecular and Human Genetics Baylor College of Medicine Houston, Texas, USA

11:oo am 1101

9:00 am - 9:30 am

Plenary Lecture 8

Osteoclast Differentiation Factor Is a Ligand for Osteoprotegerin/ Osteoclastogenesis-Inhibitory Factor Hisataka Yasuda, Ph.D. Associate Researcher Research Institute of Life Science Snow Brand Milk Products Co., Ltd. Tochigi, Japan

11:lS am 1102

COFFEE BREAK Supported 9:30 am - 1090

by Ostex International,

Inc. Exhibit



9:30 am - 1290


OPEN Exhibit




and Clemens

Ltiwik Room


Osteoprotegerin Ligand Produces Hypercalcemia, Profound Bone Loss, and Increased Bone Turnover in Both Normal and Osteoprotegerin Transgenic Mice. Casey Capparelli, Sean Morony*. Ildiko Sarosi*. Michael Kelley*, William Boyle*, David Lacey, Scott Simonet*. Cohn Dunstan. Amgen, Inc., Thousand Oaks, CA. Engineered Pluripotent Mesenchymal Cells Integrate and Differentiate in Regenerating Bone: A Novel Cell-Mediated Gene Therapy. Dan Gazit, Gadi Turgeman, Pam Kelly*, Yoram Zilberman, Ioannis Moutsatsos*. Hebrew University. Jerusalem, Israel, Genetics Institute, Cambridge. Mass. Osteoblast-Specific Overexpression of IGF-I in Transgenic Mice Increases Cancellous Bone Volume. G. Zhao*, M.-C. Faugere. H. Malluche. J. Wang*, T. Nakayama*, J. Pike, J. Fagin, T. Clemens. University of Cincinnati College of Medicine, Cincinnati, OH. University of Kentucky, Lexington, KY. Estrogen Stimulates Production of the Anti-resorptive Cytokine Receptor Osteoprotegerin in Human Osteoblastic Cells. L. C. Hofbauer. S. Khosla, C. R. Dunstan, T. C. Spelsberg, B. L. Riggs. Mayo Clinic. Rochester, MN, Amgen, Thousand Oaks, CA. Transient Expression of Cbfal in Response to Bone Morphogenetic Protein-2 and Transforming Growth [email protected] in C2C12 Myogenic Cells: A Necessary Milestone but Not Su5cient for Osteoblast Differentiation. H. M. Ryoo, M. H. Lee*, A. Javed*, H. J. Kim*, H. 1. Shin*, J. Y. Choi*, V. Rosen, J. L. Stein, A. J. van Wijnen, G. S. Stein. J. B. Lian. Biochemistry and Oral Pathology, School of Dentistry, Kyungpook National University, Taegu, Korea, Genetics Institute. Cambridge, MA, Cell Biology, Univ. Massachusetts Med. Ctr., Worcester, MA. 1998 ASBMR YOUNG INVESTIGATOR AWARD Bone Morphogenetic Protein-YOsteogenin Antagonizes BMP2-induced Osteogenic Differentiation and Is a Negative Regulator of Bone Formation In Viva. Thomas Engstrand. Aaron Daluiski*, Neil Wolffman*, Kathleen Thompson*, Ron Pederson*, Audrey Nguyen*, Vicki Rosen, Karen M. Lyons*. Department of Orthopaedic Surgery, UCLA School of Medicine, Los Angeles, CA, Department of Internal Medicine, University Hospital of Uppsala, Uppsala. Sweden. Genetics institute. Cambridge, MA.

Hall A 11:30 am


Oral Session 13


Gateway Ballroom Chairpersons:

Second Joint Meeting

11:45 am

Hall A



Homeobox Gene DIx2 Acts as a Mediator of BMP-2 Action on Chondroblast Differentiation. C. Xu, M. A. Harris*, J. Rubenstein. G. R. Mundy. S. E. Harris. Univ. TX Hlth. Sci. Ctr.. San Antonio, Texas, Univ. California at, San Francisco. California. Monitoring BMP4 Expression in Live Embryos and Adult Mice Using the -2372 to +258 Region of BMP4 Promoter. J. Q. Feng*, C. Contag, R. Dunn, J. Dai, X. Li. BLM Hogan, M. MacDougall, G. R. Mundy, S. E. Harris. Univ. TX Hlth. Sci. Ctr., San Antonio, TX. Stanford Univ. School of medicine, Stanford, CA, Vanderbilt Medical Center, Nashville, TN.